55. Kingpin
Wilson Fisk has been a criminal for a long, long time. Due to his large size, he was always picked on. Hence, he developed superb hand-to-hand fighting skills, which allowed him to defend himself and to defeat almost any opponent. That is not fat; it is all muscle. He committed his first murder at a very young age, I believe it was either 12 or 14. After the murder--for which he was never suspected--he began to build a criminal empire. Starting off by leading a small street gang, Fisk used his criminal brilliance to eventually become the Kingpin of Crime. While there has always been competition, for all intents and purposes his syndicate has been the only important one throughout the entire East Coast, and he possesses influence all over the world. To date he has never been arrested for any of his many crimes. This is partly due to his manipulative genius, and partly because he never commits crimes personally anymore. Instead, he has on retainer a huge number of supervillains to do his work for him, such as Bullseye, Typhoid Mary, and the Enforcers (Ox, Fancy Dan, Montana, Snake, and Hammer), not to mention practically every criminal in the New York area. While he has fought Spider-Man, the Punisher and even Captain America, his number one foe has been Matt Murdock, aka Daredevil, "the Man Without Fear."