Meh, I think Transhumanism is more religion than science. Not that every single thought transhumanists have ever had is without merit by any means, but I doubt there will be anything even remotely similar to what they envisage which comes to pass. Its like with all speculation, usually the world stays a lot more like it always was than the visionaries imagine.
Frankly I think its going to be a LOT harder than most people understand to just 'bioengineer bodies' and whatnot. Oddly in some sense Traveller's milieu may actually be MORE accurate than what you consider hard SF.
Some cyberpunk/transhumanist elements are already coming to pass...
Note that Cyberpunk and Transhumansim, while not the same, overlap heavily.
Prosthetic limbs with sense of touch - currently experiemental.
Prosthetic limbs with means of feeding back proprioception data. Moving towards production
RNA vaccines (currently in use)
Lab testing tissue for drug compatibility (being done experimentally)
Neural interfaces (working with monkeys since the late 00's. Lots of nasty feedback from the public)
Extrapolating facial features from DNA. (in use in anthropology, limited use in police work)
Ability to detect cancer and a number of other diseases. (Currently in use)
Exoskeleton lifting systems (currently in use in some Japanese retirement homes)
Battlefield robots (in testing) and drones (in use)
Telepresence medicine (in various degrees; surgery still experimental)
Human modified clones (Unlawful, but done)
DNA printing (doable at present, but not commercially viable yet)
Growing specific organs without growing whole clone (experiments promising; cartilage nearly consumer ready. Skin grafts in limited use)
combine knowledge of facial features from DNA, DNA printing, and modified clones and you put designer babies in reach. If specific organ growth fails, illicit clones for transplant will eventually happen.
Battlefield robots are inevitable at the present rate of improvement.
While the transhumanist and cyberpunk prognosticators are unlikely to be accurate in the sociodynamics, the tech they're presuming is coming to pass. It's absence in Traveller was noted, even in the early 1990s...
I just remembered TTNE includes a very limited selection of cybernetics in FF&S... which means T4 does, too... but not well fleshed out.
Cyberpunk was Influencing Traveller, but not incorporated into traveller. Traveller had other dystopias.