If i use twin strike, one attack at the fighter who marked me and another in his ally, the marks apply? Or no because i put the fighter as one target?
Same think to blasts and bursts, when the fighter is in the area and i hit the other allys the marks apply or not?
Marks apply a penalty when you make an attack that doesn't include the person/creature who marked you. It's resolved per attack, not per power usage.
In the case of Twin Strike, the power tells you to make 2 different attacks, 1 with your main and 1 with your offhand (or just 2 attacks in the case of the ranged version). For each of these attacks, look at who your target is. Is the target of your first attack the person who marked you? Yes, then no penalty. Target of the 2nd attack the person who marked you? No, then you suffer the penalty.
Area Blasts/bursts are different. You make 1 attack, that targets each creature in the area. If this single attack (that may or may not hit multiple creatures) includes the person who marked you, none of them suffer the penalty.
I have the other understanding: if you use a power that has multiple targets and one of them is the guy who marked you, then no penalty. Whether they be ranged, melee, close, or area attacks.

(Dungeons & Dragons)
Rulebook featuring "high magic" options, including a host of new spells.