Shades of Green
Explorer
Better yet, hand the player a Type-S Scout/Courier. A single crewmember with the right skills can run that ship alone. Just make sure that the character has the Pilot, Navigation (Astrogation in the Mongoose version) and Engineering, and probably throw in a combat skill or two as well.Traveller. More of a long shot here, but I'm pretty certain you could play Traveller with one player running the whole crew of a free trader. Generally there's one person active at a time, and it's not as if Travelller characters are particularly complicated. You could probably create a list of 'best skills' on the ship and simply use that on most occasions.
Also add a sidekick NPC with several interesting skills (Medic, Mechanic, maybe Computer or Electronics, or a Science skill in the Mongoose version)
Then start exploring the universe, one jump at a time.