Like, outside of One Punch Men, which is a parody, right?/Manga there is no mere non magical human who can compete with supernatural people.
Berserk: Guts could solo Schierke (she's basically a wizard), heck he could probably beat his entire party if they ganged up on him (which also has an apprentice wizard in it).
The thing with manga is that it tends to screw up your basic premise: Each manga tends to establish a power-system and then give everyone relevant the same system. It is extremely rare that you have a party that mixes power users and non-power users.
Jojo: Everyone has a stand.
Fairy Tail: Everyone is a spellcaster.
Hunter x Hunter: Everyone has access to nen.
Naruto: Everyone is a ninja.
Chainsaw Man: Everyone has a devil contract
Bleach: Almost everyone is a shinigami or something to that effect
Full Metal Alchemist: Almost everyone is an alchemist (or has alchemically derived powers)
Demon Slayer: Everyone has the breathing power thing.
In my opinion it is not fruitful to make comparisons with manga since D&D has become its own weird fiction. The issue is that manga basically does not have anything like the D&D wizard. It's not something that exists unless you look for specifically fiction that is inspired by D&D itself (like Overlord or some isekai series where the point is that the main character is an overpowered spellcaster).