Steve Kenson's Ad Infinitum (or Green Ronin if they put Steve in charge). Hopefully, then, Steve re-writes several of the classes, modifies some mechancis, and the default game goes back to more traditional fantasy inspirations as seen in GR's 3e Master Class series. Then, they can release specific theme supplements that support campaigns inspired by gothic fantasy, post-cataclysmic fantasy, anime (shonen and shojo), mmorpgs, mythic fantasy, YA fantasy, xianxia, wuxia, etc.
In an ideal world, I could also get behind the settings being open to Beyond Belief Games (Barbarians of Lemuria), Gallant Knight Games (Tinyd6), Basic Action Games, PEG (Savage Worlds), and whomever currently owns the rights to Cortex Prime.