Not really VTM-esqe, but here's a nasty one I'd like to see. He's an enemy from the FR campaign I DM.
Bizgurt the Gnome. Chaotic Evil 12th Level Wizard.
Pale blonde hair & beard. Lives in the Underdark, so skin is pale too. Wears a hooded robe. Rat familiar. VERY smart and VERY ruthless. Gifted alchemist, too, so uses acids & poisons in traps sometimes. Often recruits "grunt" races like gnolls and orcs as bodyguard/thugs.