I am runnig a Gamma World game right now online that is taking place in Western Massachusetts. For those who think that Massachusetts ends at Boston (and don't feel bad if you do, many Bostonians feel the same way), Western Mass is a very rural mountainous area, much like a Yankee version of Apaalachia. Some political entities I work with:
The Rectified Church of the Martyred Saints (the Wreckers): A Luddite cult of technophobic bible thumpers who rose out of the fringe polygamous Mormon sepratist sects in Mexico. They actively destroy both Digital Age and later technology and mutants. They have taken over most of the center of North America and are heading over the Appalachian mountain passes into the eastern part of the continent.
The Zootocracy of Verminont. A 'four legs good two legs bad' political entity centered in Vermont. Run mostly by Badders and Hoops, with a real hate on for humans.
The Happy Valley Collectivist State: A nation run by an AI known as O.M.N.U.S. Centered on the Pioneer Valley (Happy Valley) in central Massachusetts, right where UMASS/Amherst is located. A high-tech insular state that borgifies robots and other AIs into a huge parrallel-processing overmind. Flesh creatures live there, but are strictly monitored.
Grenfield: A city run by Grens, the peaceful green mutants with pheremone control. Very peacefull, but the Grens eschew all but Stone Age technology, relying on their pheremone control to avoid trouble.
The gangs of Nu Ork. New York has become a fractured tapestry of small tribal clans. During the Shadow Years a small clandestine group of nanowizards created the Ork nanoviral package, which was used by gangs to modify their bodies to be fearsome warriors. They have bred true over the years, and now operate a barbaric clan structure within the ruins of New York, New Jersey and Long Island.
The Sea Kings of Bahston: Boston has sunk into the Altantic, but the pirate captains that style themselves the 'Sea Kings' have built bases among the drowned skyscrapers. They sail the oceans looking for settlements to trade with or plunder (depending on their defenses!). They also battle the many mutants that now live in the ocean depths.
Anyway the thread of the game is here:
paizo.com - Paizo / Messageboards / Paizo Community / Gaming / Play-by-Post / Appalachee Jihad