In Gloomwrought, there is a nefarious organization called "The Veiled League." After the third time the DM called it "The Veal'd League" it set off nearly twenty minutes of baby cow/food jokes.
That cured him.
Cured Veal? Hope you milked it for all it's worth.
I look back on years of games that wound up dissolving into hysterics that interrupted play for anything up to twenty minutes or so at a time - and not just the games that featured characters that were deliberately comical (like a kamp captain that took pretty much anything that was said "the wrong way").
A couple stick out in my mind as particularly devastating:
Playing Cyberpunk and discussing some of the full-body conversions available: The Dragoon (Chromebook 2, pp 80-83) was mentioned - over 8' tall, 620lb, military cyborg.
I told the players that they were military only and they were equipped with a remote-kill system - in case the soldier decided to defect or desert - that could flash incinerate the living brain. And because these babies were worth so much money and often packed with sensitive equipment, there was also an internal autopilot with a recall function that would enable the machine to return to base after the destruction of the human brain.
This was explored to absurdity, winding up with a description of an 8', 620lb, heavily armed and armoured cyborg shambling through the war-ravaged streets seeking...
BRAIIIIINS!!
The idea of Zombie Full-Body Cyborgs had players and GM (me) rolling around on the floor incapable of playing for quite some time.
Most recently, in the current campaign, I decided that the Fixer the team used should have a non-standard marital arrangement.
They met the fixer - an attractive woman - and later one of her assistants, a man, whom she addressed as "babe". They drew the obvious conclusion that he was her "bit" and commented to that effect.
"Oh no," she said airily, "that's Amber and Mona's husband".
Who are Amber and Mona? the team asks.
"Amber's my wife", came the off-hand reply.
After a bit of jibing, one of the characters made some comment that prompted the fixer to say "well, Mona's looking for another partner if you don't mind sharing."
One of the players collapsed across his character sheet and lay on the floor howling with laughter. That set me off and the game was interrupted as we dissolved into fits of hysteria. My face and ribs ached and I was fighting to avoid doing something most people stop doing a few months/years after potty-training.
Took us quite a while to regain our composure and resume the game.
Later, the player told me what really set him off was the fact that the woman who was looking for a second partner was called "Moaner"...