I just don't get the mentality of "longer combats are more deadly." Say you're fighting a Duergar Xarrorn from OotA. Or actually, let's say you and your buddies are 5th level, and there are four Xarrorns (CR 2). Let's now say each of the Xarrons Enlarges itself so that it can get 2d12+d6+3 damage on its attacks instead of just d12+d6+3. You can either: 1.) engage it while it is Enlarged, suffering 50% more damage for no good reason, or 2.) fall back for the next 60 seconds until they shrink down to normal size, negating their advantage (because their puny 25' movement cannot keep up with even a normal human's ability to Disengage and move 30').
Option #2 makes the fight take e.g. 13 rounds instead of 3 rounds, but it is clearly safer.
What makes a combat deadlier has more to do with the number of decision points and critical events in it than it does with the duration.