Since Oriental Adventures was mentioned, I'd like to take a moment to let people know the recently released video game Ghosts of Tsushima has been very well received by even Japanese critics despite it being a game about Japan made by Westerners.
Now, ask yourself why.
I'm a big fan of Lovecraft, but even I can appreciate why he makes some people cringe and they have no desire to read his works. One of my favorite stories, "Herbert West - Reanimator" includes a particularly painful to read description of a black boxer that's difficult to read. Lovecraft's prose is challenging enough. Nobody should feel obligated to put up with his racism though.
My issue, primarily, is that the writer, not his work, but the writer himself, is being enshrined in the list of "Inspirational Reading" in the PHB. Not sure, really, that Lovecraft's works are all that inspirational. Note, there are tons of derivative works, lacking the rabid racism and bigotry, that deal with the Mythos, whose writers COULD be added to the list of things to read to inspire your D&D game.
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I just wanted to add another thought here.
The problem that these threads seem to have, and why
@Remathilis mentions having to walk on eggshells is the lack of focus when discussing issues.
@Remathilis mentioned removing all real world mythology from the game. Why? Is there a complaint about having Thor in D&D? I'm not aware of one and, if there is, what is the SPECIFIC complaint? "It might be offensive" is not the reason to change something. That's very much not a good enough reason to change anything. It's too vague, too broad and frankly, meaningless.
Take the Vistani issue. There is a very specific issue here - the depiction of Vistani as thieving, lazy, drunkards veers pretty uncomfortably close to the real world depiction of the Romani people, who, for hundreds of years, have gotten the short end of the stick. Now, does that mean you can never have a Vistani who is a thieving, lazy drunkard? Nope. You most certainly can. What you shouldn't do, though, is have EVERY Vistani be that. If you depict Vistani, then, well, depict all sorts, good and bad. It's a pretty easy solution to a specific problem.
Or, the OA that was mentioned above. Does this mean we can never have an Asian flavored setting in D&D? Of course not. The specific issue with the OA is the whole othering of cultures, fetishization, and the fact that the original OA book, despite purporting to be an "Oriental" book, is 99% Japanese flavored. A new Asian flavored setting needs to be more even handed, pulling from a broader range of sources, and not pretending that the culture of a billion people in the real world doesn't exist. Again, adding a disclaimer to the book is a simple and sufficient solution.
The reason people feel like they have to walk on eggshells is because people are not bringing up specific issues. No one can deal with broad, vague issues. It's not possible. We need to focus on the concrete issues where you can definitively point to this or that in the book and say, "Yes, those words right there, that sentence? That needs to change." Otherwise, it's all punching fog and frustration.
And oh I know, most of the arguments stem from homophobia, otherwise, it wouldn't be an issue. 
