Not sure if anyone still checks this thread, but I meant to write up a little post-game analysis after we finished our campaign with the system and forgot to do so. So for anyone still reading...
It actually seemed to work out pretty well, which surprises me since this was my first attempt at this kind of thing. There were tweaks made during the process and I think some of the careers are either too specific or underpowered compared to others, but that might just depend on the style of game being played. One thing I learned from this was 4E works best with an action-oriented style of campaign, but I would probably not use this for something like gritty noir stories or a pure horror campaign. I am sure someone could adapt it to other genres, but there are also so many other systems out there that work much better for specific genre. But for our action sci-fi campaign, I think it worked just fine. Has anyone else been using this, and if so, what genre and how has it been working?