The game went very well. I had five players show up and one was very experienced. He was a great help. In hindsight, had I known he was playing I would have likely not worried about which Ancient One to use because he really helped the game go well. The rest of the group had little or no experience though. The game ended about an hour or so early, with the players battling and defeating Yig. We had time for a few rounds of Dominion after that.
It seemed like everyone had fun, so I'd say it was a success.