Scott_Rouse said:Would these be new settings or current but fallow settings? For example would a 300 page Planescape, Ravenloft, or Dark Sun setting book be enough for everyone?
I would say no to those. If you offer something as well detailed and established as Planescape, Ravenloft, or Dark Sun you're only going to depress people with the fact that there will NOT be future support.
I think "one-shot" campaigns should be like Ghostwalk...but then we all know how successful that was, don't we?

Now Oriental Adventures was successful, but there are angry gamers out there who're peeved at the fact that, well, there hasn't been any OA support since.
Personally, I'd say like a 300+ page book on Planescape, Ravenloft, Dark Sun, Spelljammer, etc., with like mini-supplements once or twice a year for each setting that's like 96 pages or something.