The way I'm currently running my E6 Campaign is without Multiclassing and no Prestige Classes. I'm really just trying to make it as easy on myself as possible.
I use the Prestige classes as regular classes for my NPC's. I have no idea how difficult they are to fight (No frenzied berserker yet
)
I "buffed" so many of my classes that I have a long house rules list, but it gives my players a lot of options and abilities.
Something I found useful was to just look ahead of the classes, take SOME of those abilities and make them feats, as Ry called them "Capstone" feats.
IE a barbarian taking Indomitable Will, a Spell thief taking Absorb Spell as a feat. the only prereqs is that they are of their class level and level 6.
The reason I didn't make a lot of these Feats and just worked them into class progression is because I wanted my players to have their new abilities early to have fun
don't know how to do the "Spoilers" thing, so I posted my house rules here
http://www.enworld.org/showthread.php?p=3666681#post3666681
I use the Prestige classes as regular classes for my NPC's. I have no idea how difficult they are to fight (No frenzied berserker yet

I "buffed" so many of my classes that I have a long house rules list, but it gives my players a lot of options and abilities.
Something I found useful was to just look ahead of the classes, take SOME of those abilities and make them feats, as Ry called them "Capstone" feats.
IE a barbarian taking Indomitable Will, a Spell thief taking Absorb Spell as a feat. the only prereqs is that they are of their class level and level 6.
The reason I didn't make a lot of these Feats and just worked them into class progression is because I wanted my players to have their new abilities early to have fun

don't know how to do the "Spoilers" thing, so I posted my house rules here
http://www.enworld.org/showthread.php?p=3666681#post3666681