Look for two basic types of players. General players who contribute in several stats. These guys go pretty fast. Think Kobe with his 30/5/5, for example. Also look for spike players, someone who gives you a big bonus in a specific area you want to focus on. If blocks, look for people with high blocks. Ratliff is good here. As you draft along remember you have several positions to fill. Don't take too many guards and leave yourself short on forwards. This is just the very basics.
My personal favorite trick later on is to look for guys who have not been great in the past but who are poised for a break out year. Last your I got Brad Miller, for example. Decent guy, but he stepped it up a notch in Sac-town.