I agree, I think this theme would work much better set in the '50s or early '60s. Especially if she's a
Mad Men fan.
Or, conversely, in a dystopian future (or alternate present) akin to
The Handmaid's Tale.
Mind you, either of those change the entire game for the entire party, rather than just creating a theme for one character.
Anyone read The Ultimates? The Hulk, as depicted in that series, is a feminist's nightmare - the only mitigating factor being that he's usually too busy destroying the city to actually do anything to women, in particular. But that may give an avenue to explore - villains who either embody or take advantage of women's issues.
For example, a villain with some form of emotion control power, who instills men with strong misogyny, or women with self-destructive self-esteem issues. Villains who embody body image problems, or eating disorders, a corporate villain who's major vehicle is women's magazines. A drug ring pushing a new drug that works all-too-well for date rape? A deranged villain with mental powers who commits psychic abuse.
Or, again, returning to the Ultimates - Henry Pym there is not so much a women-victimizing villain as he is a hero who beats his wife.
Any and all of these can be very, very touchy subjects. Make sure the entire party is okay approaching these issues before you bring them up in game.