Okay, here's my re-thought Meta-Plot for my campaign, now featuring Sothillis, Cyrvisnea, House Extaminos and Tuan-ti gang, the Sothillian Empire, Hlondeth, Ormath, the Church of Selune and Shar, The Coucil of Six and the rest of Amn, and it's neghboring country Tethyr.
The Insidious Threat
Folk far and wide have heard the plea of the Council of Six, the ruling body of Amn. A mated pair of ogre mages, Sothillis and Cyrvisnea, have forged an unholy alliance consisting of goblins, kobolds, ogres and hill giants and have sacked the city of Murann and have declared it the capitol of the Sothillisian Empire - and the Council of Six wants it back. There has already been some further strife for Amn, since two southern cities, Riatavin and Trailstone, have deflected to Tethyr, citing better protection then that which Amn provides. Soth and Cyr have coerced the Alchemists Guild into creating potions and alchemical items for the armies, which are now well-entrenched in Murann and the surrounding land. This is not to mention that one of their own was in Murann when it was sacked, and is now either a captive of the ogre mages or dead.
The army was backed by the church of Shar, who snuck into the city under the cover of dark and assassinated many of the cities' arcanists in their sleep. The Sharrans currently reside in the (former) temple of Selune, the Moonmaiden's Hall, and have defaced this once-hallowed temple. Meanwhile, the church of Selune relentlessly crusades to regain the city, and thus their temple. They do not yet have an clue that the church of Shar, perhaps one of their greatest mortal enemies on Faerûn, have taken up residence in it.
Soth and Cyr assailed Murann in hopes of finding the lost cache of magical weapons, as well as to acquire the vast quantities of Maztican gold in the ships docked there. While they were successful in getting the gold (and thus funding their many exploits) they were unable to collect the weapon cache.
In the Vilhon Reach, House Extaminos secretly backs Soth and Cyr, and has commissioned the creation of a permanent
portal between Hlondeth and Murann, to easily transport poisons, gold and scaly-kind mounts to the Sothillisian Army; there is no love lost between Hlondeth and Amn. In public, they stay neutral on the subject of the Amnian Crisis, however.
In the Wetwoods, further to the west of Hlondeth, the lizardfolk have risen up, paid off by House Extaminos, and are attacking Ormath, a city friendly with Murann, with a fury. House Extaminos has always competed with Ormath for trade, and see this as a great opportunity to back the Sothillisian Empire by doing any with a threat to it, as well as ensure themselves a larger portion of the trade.
This southern section of Faerûn is rife with intrigue, deceit, and the rumble of war drums, and perhaps it is only a few lone hereos who can help...