Long live Shadowrun!
No, it's not d20 system... no biggie though.
It's played more or less like any other game...
Played in the style I consider proper, it's alot like playing out the Matrix (Sorta), or Mission Impossible(sorta), or Demolition Man(sorta), or Judge Dread(sorta), or Virtuosity(sorta), or... Yeah, it's sorta hard to explain. It's got a very nice feel to it, though... if you wanted to see one movie to get a feel for it, I'd suggest maybe Demoliton Man, but edit out the cheese and cornieness.
Yes, it's a lot of fun.
It's not exactly like Arcanum... first of all, the technology is a lot more advanced

But it also doesn't have the same... mood, I guess, of Arcanum. Technology is a bit more domiant in Shadowrun, not like Arcanum where it was just one possible path.
If you have played Rifts before, imagine that, but without all the stupid, ubermunchkin, crazy, out of place, etc stuff that Palladium throws in with every new supplement.