That's a reasonable question, but in the same way that you can run 1e without much in the way of PC deaths (I was in three year-long 1e AD&D campaigns in the mid-1980s in which no PCs died, and these were not Hickman Revulsion adventures) you can run 5e to be extraordinarily lethal. The defaults don't matter so much as the range, I think.I think the issue here is: how far beyond the game's defaults do you need to go to challenge the PCs at a potentially lethal level?
EDIT: All those are the general "you," to be clear.
			
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