Well, it's mostly bad because (assuming you intend to use the two side of your hybridness evenly), you miss out on the major class feature you get from your rogue half 50% of the time.
My favourite Hybrid option that I'd statted out up to 10th level was, for the sake of argument, what I called "Jedi Knight"
I've only got PHB1, but essentially it is a Fighter/Wizard hybrid.
Warlock/Swordmage (I made a Shielding SM/Infernal Pact Warlock with a focus on the White Lotus feats and a "damned if you do, damned if you don't" concept. Awesome)
Fighter/Runepriest - its as if this combo was made in Dwarf Heaven. Awesome coolness and the Runepriest looses very little. Has good AC in general, since the only lost item on the armor side are heavy shields.
Overall, Warlocks, Runepriests and Shamans make VERY good hybrids in my view since they loose very little of what defines them.
I don't know how a half-orc monk/warden would go, but for a defender striker you might want to keep in mind the half-orc tempest fighter/ dual wielding ranger. Dual Strike and mark two targets, Twin Strike and unload two attacks and quarry on a single target. Off hand strike for a third attack. When you get rain of blows... well just imagine the combo. You can put 13 in Wis and multiclass into avenger for copious mounts of d20 rolling for two rounds (solid!). With Pass Forward and Skirmishers stance...ouch. Anyway I could go on, but in a nut shell, especially with Pit Fighter PP it's a pretty deadly combo.
You don't seem to be looking for a defender leader, but a runepriest/ battlerager fight is hard to beat. I went human for the extra at-will; so with Brash Strike, tide of Iron and Rune of Diminishment he has some pretty decent flexibility. Plus when he hits he gains 3 temp hps and when he gets hit he does +3 dmg.