So far ~30% of this thread answers the OP in good faith, the other 70% is talking about things tangential or orthogonal to the OP. Just another day on the interwebs I guess...
For me, here are some publishers of games I like, I'm going to think out loud whether them winning the Super Lotto and buying controlling interest in D&D would be like...
Burning Wheel HQ - hmmm. Thor and Luke at the helm of D&D? Well, Inspiration and the flaws/ideals/bonds/etc of the background may actually have some mechanical use. Maybe in some way tie into the advancement system in some way. Social interaction would actually have some rules that wouldn't be boring or depend on the GM to make ish up. Might get too complicated. Overall, rank that as a B+
Lumpley Games - well, I love Meguey and Vincent's Apocalypse World and all that came after in that geneology of games, at least in gestalt. However I'm not sure how much swearing I want in my D&D, and how much anarchic spirit D&D can handle. Let me be clear - I don't think the Lumpley principals have ANY interest in recapitulating PbtA rules into D&D - that ship sailed a dozen years ago. But I"m pretty sure once Vincent and Meguey figure out what they want D&D players to experience while playing the game, they could deliver like BOSSES on that promise. But I doubt the current group of players would want that, at least 95% of them. So A- for me personally, C- for the D&D brand as a whole.
Dire Wolf Digital aka Cortex Prime - Cam Banks and company would do an amazing job of modularizing D&D and also making it cross compatible with a bunch of other genres. Want D&D Supers? Done. D&D Noir? Done. Personally, from a pure gaming standpoint, I think a Cortex Prime D&D would be the best D&D ever. Existing fans may even be able to adjust - although it would be a starker change than the one from 3e to 4e... New fans I think might pick up Cortex D&D easier. I'd give this an A- overall
Speaking of cross-genre, what about Steve Jackson Games (GURPS) or Pinnacle (Savage Worlds)? Well, I've played GURPS many years ago, and frankly that system feels super dated and clunky - and very poorly suited for the streaming/AP world that's required for an IP like D&D. Savage Worlds I"ve actually never played, but I have heard good things about SW Rifts. Maaaaaybe it would work? Exploding dice are always cool.
Last one, and of course I'm saving my A for the end is Arcane Library. Shadowdark is kind of already the D&D we needed, deserved, and didn't even know we wanted. Maybe a "brighter, more heroic" version called DayLight or something could be released? I don't know, but I would trust Kelsey Dionne to do the right thing, first, last and to the end.
So to recap this tl;dr:
BWHQ: B+ - intriguing, but "we're not ready!"
Lumpley: A-/C- Niche play, but "we're not worthy!"
Cortex: A- I could see this working! And yet...
GURPS/Pinnacle: I don't think so
Arcane Library: Straight A - yes please