A lot of it is the attitude of the parents. We never had a problem with our first. My wife would duck behind the couch when it was time to nurse, but otherwise no big. When the second came along, it was a bit more -- switch off tasks until their bedtimes match up, then a bit of extra time tucking them in, etc.
The real challenge is that we've now got three under five and I'm the GM, so my wife is on her own. Only the last month or so has been bad, with the youngest needing needing fed the first half-hour and the last half-hour, with bedtime for the other two midway through. She's missed a chunk of the game the last 3-4 sessions, but we were largely doing in-town/downtime/bookkeeping stuff. Soon enough, though, the feeding schedule will change again, with more solids, and an earlier bedtime (about the same as the others), so we may be able to just call a mid-point break and tag-team all the kids.