There is a Barbarian build (Whirling Slayer) built around using two weapons - you could probably go that route, possibly multiclassing ranger, and picking up appropriate skills, and end up with a damage power-house who still is a skilled explorer with decent flexibility.
As others have mentioned, the Shifter race is pretty much the way to go to represent a PC with lycanthropic ability.
Also, on a side note, a Dragon article from a few weeks back presented a variety of backgrounds for Shifters from the Forgotten Realms, including one for a group of, essentially, elven shifters descended from an elven werewolf. So if that was a key part of the character concept, the option for it remains.