I've been reading Megatokyo for over a year now. For the first several months, the strip was very, very funny, with lots of clever jokes about anime and video games.
Unfortunately, it's really gone downhill since last spring/summer. Instead of being funny, the strip focuses on the girls who have crushes on Piro. Too often I've seen strips that were nothing but a girl clutching a plushie and thinking "What should I do?" Occasionally, there is a funny strip, but it almost always stars Largo.
I also agree with the guy who posted above; I haven't ever seen a stick-figure strip that was even remotely entertaining.