Drat.
I hate it when I find a Paranoia thread when someone has beaten me to all the good jokes.
Biggus, you mean you thought you were telling "good" jokes before?
Shut up.
Anyway....
* I agree with "El gato del pirata". 2nd edition is best. Avoid 3rd and 4th edition at all costs.
* Get the "Dragon" CD-Archive, or find issue #106. There is a FANTASTIC article called "Notes from the Underground: tips for Paranoia traitors". It's a fun read and I can not reccomend it enough.
* I've said it before and I'll say it again: Paranoia is the best, truest role-playing game out there. You can not-roleplay in D&D. You can not-roleplay in Vampire. If you try to not-roleplay in Paranoia, you'll be turned in for treason by the other players!!!!. Take that Mr Rein*Hagen!
* Stay alert! Trust no one! Keep your laser handy!