I used a slightly varied version of Noble Rot, my PCs just burnt the whole place down after sledge hammering out the corners of some supporting walls. I had described lots of old withered vines and large pallets of mulch, so they had plenty of fuel to work with. Even though one of the PCs had rightful claim to the place, they said "who the heck would ever drink a wine made from this place ever again?" I am not sure if it was just that the variations I put in did not give a compelling reason to explore or cleanse the place, or if it was an issue with the adventure itself, I can't rightly remember.