I'd make Perception a passive trait and make it all active skill use into Investigation/Observation maybe combine Insight into Observation too
Combine Athletics and Acrobatics into one skill that can be used with Dex or Str or Con (Endurance)
Combine Persuasion (Cha), Intimidation (Str) and Deception (Wis) into Persuasion Skill
Lore (Arcana, History, Nature, Religion, Culture/Language) I'd treat as Tools
Medicine/First Aid - should be more important by nerfing healing spells (cure only replaces HP \, first aid is still needed to close wounds and stop infection)
Stealth could include slight of hand I suppose
Animal handling could be combined with Nature as a Lore