IOW, when the party asks the crotchety old man at the bar about a bit of local history, he can spout off:
"Three Brands for the cattle-kings yonder by Big Sky,
Seven for the Shorthorn-lords in their halls of stone,
Nine for dairymen doomed to die,
One for Señor Oscuro on his dark home
Out in cold Chicago where the stockyards lie.
One Brand to rule them all, One Brand to find them,
One Brand to bring them all and in the railyards bind them
Out in cold Chicago where the stockyards lie."
In a township game, you have the usual horde-of-orcs, corrupt chamberlin, quest for the lost mine type situations, but reskinned for the Western setting.
IOW, Indian attacks, cattlebarons vs sheep ranchers, land grabs due to the railroad coming through/feeding & water rights/valuable mines (gold, silver, tin, lead, iron, nickel, turquoise, salt & more)*, runaway slaves, Chinese labor revolts, opium riots, bank robbers & Pinkertons, settlers & Manifest Destiny, frontier exploration & dangerous passes ("Donner, party of 12...er...10...er 6...").
* If you pick up an issue of Rocks & Minerals magazine or watch a few episodes of Cash & Treasure (w/Kirsten Gum (yummy hot!!) or Becky Worley), you'll find a lot of info on where various notable mines & strikes were and still are, and when they were discovered.