Crimson Longinus
Legend
How I usually run is that social skills generally don't work on PCs and certainly not in the same way than on NPCs. Though deception can work in a sense that if the NPC beats the PCs insight, I inform the player that they do not detect any signs of lying and the NPC seems sincere. But of course the PC knows that some people simply are good liars, and can decide to not trust the NPC nevertheless.
Now I could see intimidation and persuasion working on PCs so that they would place some sort of brief debuff. The NPC successfully intimidates the PC "Don't do X or horrible things will happen to you" so the PC has an disadvantage to do X. This I feel is far better than the result just being "you can't do X." That being said, I probably wouldn't do this. Perhaps if the NPC was somehow legendarily intimidating/persuasive/etc. But usually such creatures already have some special power to represent that.
Most of the time I just try to take the NPCs social skills into account when I portray them. NPCs with good persuasion are portrayed in a manner that they come across convincing, intimidating NPCs are portrayed as scary etc.
Now I could see intimidation and persuasion working on PCs so that they would place some sort of brief debuff. The NPC successfully intimidates the PC "Don't do X or horrible things will happen to you" so the PC has an disadvantage to do X. This I feel is far better than the result just being "you can't do X." That being said, I probably wouldn't do this. Perhaps if the NPC was somehow legendarily intimidating/persuasive/etc. But usually such creatures already have some special power to represent that.
Most of the time I just try to take the NPCs social skills into account when I portray them. NPCs with good persuasion are portrayed in a manner that they come across convincing, intimidating NPCs are portrayed as scary etc.