What I've been working on starts with the Core d20 mechanic and then completely rewrites everything else. I made a whole new set of classes, reworked the Attributes and made changes to many skills and combat stats, changed how class abilities work and are gained, whole new magic system, changed combat significantly by changing how rounds, attacks, and movement work, then I overhauled how items are used and equipped. Then I had to write a new book of spells to be used, rewrite and rebalanced every feat plus about 100 more that I thought it needed, AND THEN fill out an armory. and continue the bestiary.. >.>
It's meant for nearly any fantasy campaign (but realistically my own - Niira & Oryth), including super-heroes in a fantasy world. Right now I'm adding some scifi bits for a futuristic campaign (my HeavyEPIC setting). So from the ground floor it was meant to run nearly any genre. I even have a file on dragonball races lol.
A name for something that tries to be all-encompassing, modular, and seriously not lame seems escape me at the moment. I liked Saga, Lore, Sage, Core, etc., but alas they were all established gaming names or didn't really stick.