It's kind of funny. I saw this thread and like some threads do, it really got me thinking. And over time, I decided I can't think of a single IP I'd like to see drawn into the 5E world. I just saw the movie Legend last night (after watching it on VHS about 100 times) and it definitely would work as a 5E setting. But is that exciting? Would I be picking that up? Probably not, except for as a source of lore.
And that frustrated me because I don't think I've ever thought that way, even during the 4E days when there were far fewer IPs that would be appropriate to have the system explore.