Just as a minor thread-hijack - can anyone remember the last time a setting reinvention of the 4e FR type actually *worked*?
In D&D? FR 2e. I
hate the Time of Troubles and the resulting major changes in the product line, but I'm in the minority. FR 2e became the most popular D&D setting for the better part of two decades. Until it was supplanted by FR 3e (which made some changes, but relatively minor ones by comparison). It's too soon to tell whether FR 4e will follow suit and be another hit but, if history is any indicator, it likely will be.
New World of Darkness. A lot of old WoD fans don't like it but enough people
are buying it that it continues to generate profit and spawn new product lines. I think it only
seems less popular because playing vampires and werewolves is no longer the novelty that it was in the early 1990s and, so, the nWoD doesn't get as much attention outside of its target demographic as the oWoD initially did.
2300 AD. Not technically Traveller by design, though originally billed as Traveller
and still plenty popular with many hard core Traveller fans as an alternate setting for the game. In fact, it actually has
more fans than some reiterrations of the official Traveller setting (such as Millieu 0) have.
Deadlands: Hell on Earth was
very popular in its heyday and was, quite literally, a revisioning of the original setting via timeline progression. It took the Weird West into the post apocalypse (making it the Wasted West), introducing killer cyborgs, mutant doomsday cultists, and Mad Max road warriors along the way.
Rifts Earth is a special case, but it qualifies, IMHO. Nearly every RIFTS supplement
drastically advances the timeline, redefines the cutting edge of technology, or alters the political climate of the entire setting through the medium of whatever region it focuses on. Supplements like Juicer Uprising (World Book 10) and the Coalition Wars series are great examples of this setting revision/updating.
There may be other examples, but those are the only ones that I can think of, currently.