The VOIDRUNNER'S CODEX is coming! Explore new worlds, fight oppressive empires, fend off fearsome aliens, and wield deadly psionics with this comprehensive boxed set expansion for 5E and A5E!
The smart money is on the Forgotten Realms. I wouldn't mind a place in that setting we have yet to see in video game form though.
Barring that... Eberron or Dark Sun would be my thoughts.