I'd replace Sorcerer with Warlock, Beguiler, Warmage and Dread Necromancer.
Replace Fighter, Monk and Paladin with Warblade, Swordsage and Crusader respectively. This might still require it's own book to contain all the mechanics.
Replace Rogue with Factotum.
I'd keep Bard, Barbarian, Cleric, Druid and Wizard.
I'd do away with the Ranger.
I'd add Marshal.
I like Psionics, but they would still need a seperate book.
That's my 2 copper.
EDIT: Healer, Duskblade, Archivist, Dragon Shaman, Dragonfire Adept, Incarnate, Totemist, Binder, Scout, Swashbuckler, Shugenja, Wu Jen and the NPC classes would all exist as options in other source books.
Favored souls, Hexblades, Knights, Ninjas, Samurai, Shamans, Spirit Shamans, Spelltheives, True Namers and Shadow Casters would all go away.
Not sure where I stand on the Sohei.
Did I miss anything?