My LGS's: (Broward county Fl)
Twisty Land: 2 minutes from my house, this is dedicated to CCG, CMG, C*G, whatever! The store isn't big, except for the 4 acre's of tables for the kiddies. The D20 section is a 5' long shelf near the door, which has the newer releases from WotC only. There's one guy that's fairly informed about release dates, so once they transfer me to him I can get the info, and they hold it for me. (Though, by "hold it for me" I think they just don't put them on the shelf right away. So if you called for one, they go in teh back and grab one, "just for you!"

Nice enough shop, though the guy did try to engage me in conversation once, about his rogue... Luckily I made it out.
Past Present Future: 45 minutes away, all the game books are in bags, which you can take to the counter and they'll open it for you, while supervising... I'm 31, that's not something I'm going to do, it's a waste of my time and theirs. they have a 40% off section that's a bunch of old stuff, none in bags, and it's fun to skim that section. (Edit: and the shelves are horrible. They are about 1 foot deep, and very low at the bottom, so to see the books on the bottom shelf, which are face out not spine out, you have to practically lie down!)
Local book chains (Waldenbooks, Barnes & Noble, Borders): I usually frequent the local Borders (across the street from Twisty Land) when I want to read through a book before purchasing. For whatever reason, if reading a book in a particular store is the reason I'm buying the book, I'll buy it at that store.
So, anyway, lately if it's something I know I'm buying, but don't need right away, I get it from Buy.com. They're cheaper than Amazon, offering the same free shipping. Walmart.com charges shipping on top of the same price as Buy.com, so that's useless to me, especially when you add in Walmart charging me sales tax.
For stuff I HAVE TO HAVE RIGHT NOW, I go to Twisty land, if I'm near PPF, I'll poke through the stacks, but don't go there on purpose.
www.stiggybaby.com is for Shadowrun and other assorted Can't Find stuff.