The Three Flavours Cornetto trilogy - Shaun of the Dead, Hot Fuzz and The World's End. Just the perfect mix of comedy and being both and ode to and satire of the three genres of film. They can't be improved on.
Kung Fu Panda - Perfect blend of action, comedy in an animation package, it was this or Toy Story and hard to pick between them but everyone had mentioned Toy Story already.
Pirate of the Caribbean - Visually stunning, amazing stunts, fantastical story, and amazing CGI, Johnny Depp was born for the role.
Captain America - First Avenger, Winter Soldier and Civil War. Probably some of the best Marvel movies made, it was close with Guardians of the Galaxy.
Man with No Name - I thought I pick a really classic one to finish off, a young Eastwood already a commanding presence on the screen, excellent score, setting westerns don't come much better.
Honorable mentions - Alien 1, 2 and 4. Back to the Future, Toy Story, Terminator, Spiderman (of all eras).
And of course Highlander gets a mention even though they never made any other movies.