The VOIDRUNNER'S CODEX is coming! Explore new worlds, fight oppressive empires, fend off fearsome aliens, and wield deadly psionics with this comprehensive boxed set expansion for 5E and A5E!
I liked Battlelords of the 23rd Century for hard sci-fi. It certainly had that Aliens vs. Predator/Starship Trooper feel. It's no longer in print, but you can usually find the source books cheap on Ebay. It has a fairly decent cult following.
The 2300AD suggestion was excellent as a campaign resource. You don't actually need to use the old GDW rules, you could use just about any ruleset you liked. But the Kafer War materials are great scifi us vs. them military campaign.