Wow...I think this is by far the most complex stat block I have seen so far, and it is only for one of her forms.
It's not that complex really. The tactics would be:
[sblock]Round 1, Teleport 8, pop Impenetrable Darkfire for CA and defense, Attack with Scourge, slide target to where they can be most effective, then action point and use Insidious Poison to get an extra attack. If someone hits you (which should be difficult without AoE's) without dazing or stunning, use dominating Rebuke.
Round 2, if not stunned or dazed, then give someone a kiss and use Insidious Poison if it recharged. If no recharge, Scourge someone, Action point, Scourge again. If you didn't need your move, pop poison strands as a minor. Then Impenetrable Darkfire drops, remember to use dominated minion before being forced into Form of the Spider Queen.
[/sblock]
I think it will probably be a fun two rounds. Note the 2 action points, so you'll have an action point to spend practically every turn. There's hoping your other form has 2 AP's as well.
If I wanted to make the fight a little more epic, I would give her a few companions, maybe a leveled up Balor or something, maybe a few Mezzodemon Shocktroops. Her damage potential when she is not dominating is rather low to be any significant threat for the two round pre-fight.
I guess if the Spider Queen Form is statted as an actual Solo, rather than another Elite, then the pre-fight suddenly makes more sense, to force PC's to blow their nova and stun powers in those first few rounds, and have a real fight afterwards.