The first paragraph of this is kind of a reality denial and illustrates the impossibility of what Paizo is trying to do. There is, in some meaningful way, no such thing as "The Pathfinder RPG" with its own, independent existence. What I mean is that, Pathfinder fundamentally is nothing more than a modest modification of D&D 3.5; no amount of supplements can change that. PF2e is an interesting game, but it's not a new version of D&D 3.x. The big major revision to that system, as far as the market is concerned, is D&D 5e. For "a new version of Pathfinder" to really be embraced by the market as one, it would have to be a lot more like the 3rd edition of D&D than not.
Well, it's a lot riskier, which is why we rarely see new things come out of established companies. Whatever the next Vampire, Traveller, or D&D is, it probably won't be made by any of the current players.