I've considered doing this before but never really got it out of the "thinking about it" stage.
Not 100% sure which analogues I'd use but maybe I'd have dragonborn replace humans as the most populace race. Kobolds would replace gnomes, specifically tinker gnomes. I have an image of kobolds as artificers that are the equivalent of wild magic sorcerers, they love making things and often those things blow up.
Yuanti will always be the bad guys, essentially the snake men from Hyboria, except they're out in the open as the rise of man has not yet driven them underground.
Lizardfolk are the primitive cousins to dragonborn or perhaps they just prefer a nomadic primal existence over the cities of the dragonborn. In fact, that would be cool to see tribes of nomadic lizardfolk with giant lizards as pack animals.
This would be a setting where I'd also be keen to have dinosaurs. I normally don't use them unless I'm including a lost world section of the setting. I think I would also want to update saurials to 5e. I kind of see them as wise philosophers, I'd probably create a loose caste system for them where each specific type of saurial gravitates to specific areas, similar to their 2e class level limits. They'd also have a reputation as being some of the best spellcasters in the world.
And as a bonus setting, after playing in the scaled world, you can advance the setting thousands of years to a point where man has risen and spread out, great dragonborn and yuanti empires have crumbled, and now their former homes become sites for humanity to explore and plunder.