A D&D farming simulation videogame shouldn't be very hard about the lore. It could be a domain of delight within the Feywild, with a lot of halflings and gnomes, but if you want something with more survival touch, then I advice a Dark Sun survival where the main character is a fugitive ex-slave. Birthright could be perfect for a stronghold management/economic strategy/city-builder videogame.
* What if Epic Games creates their won VTT for Fortnite: Creative Mode 2.0?
* Before I (almost) only played Fortnite, but after some bugs I couldn't load the game, then I stopped and now I only play Shop Titans, a shop management simulation.