NO MORE LEVEL DRAIN - Good. I always thought it was metagamey in the extreme, and a real PITA to deal with anyway.
NO MORE (temporary) ABILITY DRAIN - Neutral- I really didn't mind ability damage, but I'll hold off and see what they plan to do in its place.
NO MORE SAVE-OR-DIE - Good- nothing sucks more than one bad roll taking you from kicking to kicked-the-bucket.
NO MORE ETHICAL ALIGNMENTS - Neutral- dependent- I always thought the alignment system was a litte too abstract anyway, and subject to far too many arguments.
SNEAK ATTACK ON ANYTHING - Leaning Towards Good- that said, I'm not sure if it would apply to absolutely anything. While i can see the argument for SA some undead and constructs, I have a hard time with incorporeal creatures or oozes being Sneak Attacked
FASTER GAME MECHANICS - Good- if they can deliver
FASTER (N)PC CREATION - Very Good- One of my big gripes about 3.5 was the NPC prep time.
NO MORE EXCESSIVE AMOUNTS OF MAGIC ITEMS - About Time- I am pretty sick of the magic item trade that has taken over the game, and PC's reliance on soooo many items, plus the tragedy of having most players rather have their characters die than lose an item.
NO MORE (or less) VANCIAN CASTING - Neutral/Leaning Toward Good. I'm liking what I'm hearing about 4e's magic system
NO MORE SPELL SCHOOLS - Neutral- waiting to see the results
FOCUS ITEMS - Neutral- Not enough info to go on really
SKILL SYSTEM REVAMP - Good- I always thought there were many skills that were unnecessary, or that could be combined with other skills.
BASIC RACES CHANGES - Neutral- I had no love or hate for the gnome. I actually like the idea of Dragonborn (remind me of Dracha from Arcana Evolved), and Tieflings have been around since 2e.
RACIAL PANTHEONS GETTING THE BOOT - Good- I'd rather not have the clutter of gods needed to address each specific race's needs anyway.
ELIMINATION OF PRESTIGE CLASSES - Good- It was an interesting idea, but poorly executed and so easily abused. I only hope the alternative is better.
EFFORT TO BALANCE FEATS - Good- if they manage to do so
PARTY ROLES - DEFENDER, LEADER, ETC. - Neutral- Stuff that's been unofficially used for years anyway.
POINTS OF LIGHT SETTING DESIGN - Good- I like the feel of those kinds of settings myself
LACK OF BACKWARDS COMPATIBILITY - Neutral- not really concerned. If I wanted to play an older version of D&D, I'll play that version.