The only thing I'm going to add to this is something that Ryan Dancey said many moons ago, when discussing why WoTC wasn't doing Ravenloft, Dark Sun, Planescape, Spelljammer, Dragonlance, Mystara, or (really) Greyhawk anymore.
Only a small subset of gamers buy world settings, and anything branded as being "for" a world setting is often passed over by buyers since they feel it won't be of use to them.
If Wizards is (mostly) getting out of the world setting business, then it only stands to reason that 3rd parties will find it rough going. There is a proliferation of world settings out there right now, and I'd bet most are faring poorly, in comparison to the "generic" D20 products. I'd love to see sales figures supporting or not supporting that idea, though.
World creation is a labor of love, and it should be done for it's own sake.
However, having a nicely produced product ("selling" or not) could help you get actual, paying work, if that's what you're interested in. As Colonel Hardisson pointed out, his independent film didn't sell worth beans. However, it's possible that if it was any good (even just visually speaking, or for the script) that it could get him in the door of a larger production. Today's films are littered with actors and directors who got their start on low-budget independent or student films. I could name dozens of names, including a lot of very big stars in the field.
It's possible that this could be used to help you in that way. But it's up to you. And guilt trips laid on us isn't a great way to build a consumer base.