Stripped of the setting, it's hard to imagine many people signing up for Slave Catcher: The RPG.
Yeah I kind of wondered why so many people seemed keen on the idea. It's like, did people not watch the movie? From this thread - evidently they did not, or profoundly misunderstood it. And it's not a subtle movie, or an underdiscussed one, either!
You're a monster who has to survive by doing bad things.
There's a key difference, though, isn't there.
Has to.
Vampires in VtM have, depending exact edition, basically three choices:
1) Find a way to feed.
2) Don't feed and go berserk, probably killing a bunch of people.
3) Attempt to die in a fire, but possibly go berserk and fail to do so and maybe kill a bunch of people.
Blade Runners have two choices:
1) Be a slave-catcher.
2) Don't be a slave-catcher, go get some other job.
That's not exactly the same level of dilemma, is it?
Further a Blade Runner presumably chose to get into that line of work, whereas an awful lot of vampires either didn't choose at all, or were not exactly given the full information before they were turned (and may well have been turned when they were pretty young and dumb, indeed that's kind of the most likely time), and importantly, there's no going back. Further still, feeding in vampire is not necessarily a huge focus of the game, and certainly in the editions I'm familiar with, is often largely off-screen. It's also not true to say all siren vampires are "feigning" sex or are "serial rapists", that's a distinctly VtM
Revised viewpoint, in 1E and 2E that certainly wasn't clear-cut, and I'm skeptical 20th Anniversary follows Revised here (I mean I'll believe you if you say it does, but does it?), though I don't know which way 5th went - but that is the sort of edgy thing 5th would be into so I could believe it - then again, 5th being edgelord-y even by VtM standards is part of why its popularity is... limited. To be clear, Revised's maximum body-horror, maximum personal horror approach is valid, but I don't think there can be any question that, had VtM 1E gone as hard on the same themes, had the same lore, and so on, it would not have been nearly as successful (there were always some groups who ran it that way, but I think they were fairly small in number compared to the "intrigue/politics/mystical mysteries" groups and "trenchcoats and katanas" groups - certainly the sourcebooks and adventures supported the latter two, and not the former, in 1E/2E).