While I understand this, especially if making tweaks, one of the reasons I like DMing in published settings is that the players could know as much as I, and we explore it all together. They may as a result know more than a PC does, but at same time have a better likelihood of knowing what a PC would than starting afresh in a new unknown world, where they know less than a PC would.How do you approach the setting? What I like is in; what I don't is not. I twist, change, pick and choose at my own liking. That way, the long history ceases to become a chain and becomes a toolbox. I lean into the aspects that interest me, steal from other settings, change bits here or there that I think make it more evocative, etc. I do forbid my players from browsing the FR wiki and enforce such forbiddance stringently; any knowledge they get about the setting comes from me.
I dont use FR per se, but its so expansive that I will refer back to its Lore and use its locations, factions and characters and set pieces as inspiration for my own gamesWhy? I run games in FR because it is a near-endless spring of ideas. Many brilliant designers, creators, novelists and worldbuilders have labored on FR, each adding a twist or bit, and now I'm spoiled not only for adventure ideas but by variations of the campaign setting. There's a kernel in each major character, nation, faction, or region that will interest you, even if you discard the rest.
It’s fun, and most of my players have some aspect of the setting they like.A positive post about this setting which is simultaneously legendary and divisive. Over the decades we've read endless posts about the high level PCs (overblown, imo), the world shattering events, the neverending pages of canon that weigh the setting down etc. etc.
Yet many people still game here. Some never left.
So for those of you who still choose to run their games here:
1. Why
My FR continuity pretends 5e didn’t happen, and continues on from 4e, with some tweaks like pretty much no spellplague leftover areas, and it’s less points of light. Basically the vibe is similar to the 5e realms but the canon is closer to 4e. Netheril hasn’t fallen and is instead in the midst of rebellion, but Cormyr doesn’t have the 4e edgelord changes or additions like a prison city.2. How do you approach the setting (everything is in, stick to one edition, gray box only etc.)?
It isn’t, but it’s been one of many for about 20 years.3. How long has it been your campaign setting of choice?
The 4e Neverwinter book, the Baldur’s Gate games…4. What are your favorite game supplements?
The Everis Cale books are good, and I like the ES De Bie books, and Elaine Cunningham, and others I’m forgetting. The Elminster books are fun.5. Do you like any of the novels? Which ones? And do you use the novels for game material?

(Dungeons & Dragons)
Rulebook featuring "high magic" options, including a host of new spells.