Okay, the Weave is gone, but what about the Shadow Weave? Is Shar the new default goddess of magic? Also, wasn't the purpose of the Chosen to anchor the Weave so that - if Mystra died - it would somehow survive (in some form, at least until another took up the mantle of deity of magic)? 
Also, are they still using the Roll Of Years? If we skip a whole 100 years to 1485 (or whenever), then it gets even crazier. We skip the so many interesting sounding years!!
1385	Blue Fire
The following years just sound so interesting! Allusions to Shar twice, the Phaerimm, the Shades, the Seven Sisters, and the Shalarins (whatever they are). If we only jump forward 10 years (to the Year of Blue Fire), it seems that the seven sisters will survive for at least another 40 years, as 1425 is named for them. 
1406	the Blackened Moon
1410	the Eight-legged Mount
1417	the Phaerimm's Vengeance
1419	the Empty Necropolis
1420	the Dark Goddess
1422	the Advancing Shadows
1423	Thundering Hosts
1425	Seven Sisters
1427	the Shalarins Surfacing
1428	the Elfqueen's Joy
The 8 years of Silence (1432 - 1439)
1432	Silent Thunder
1433	the Silent Departure
1434	the Silent Crickets
1435	the Silent Bell
1436	Silent Shadows
1437	the Silent Flute
1438	Silent Waterfalls
1439	the Silent Tear
These years sound VERY interesting. 
1440	Azuth's Woe
1441	Resurrections Rampant
1449	the Godly Invitation
1450	Holy Thunder
The odd 5 years devoted to elves.
 
1461	Three Goddesses Blessing
1462	the Elves' Weeping
1463	the Reborn Hero
1464	the Six-Armed Elf
1465	the Elven Swords Returned
The 12(14?) years devoted to circles.
1466	the Mages in Amber
1467	the Three Heroes United
1468	the First Circle
1469	Splendors Burning
1470	the Second Circle
1471	the Plagued Lords
1472	the Third Circle
1473	the Heretic's Rampage
1474	the Fourth Circle
1475	the Final Stand
1476	the Fifth Circle
1477	the Purloined Statue
1478	the Dark Circle
1479	the Ageless One
After 100 years, this is what we have to look forward to: Nether reborn? 
1484	the Awakened Sleepers
(1485	the Iron Dwarf's Vengeance)
1486	the Nether Mountain Scrolls
1487	the Rune Lords Triumphant
What happened that Dwarvenkind was considered dead? Are dwarves somehow suddenly made fundamentally different? 
1488	Dwarvenkind Reborn
I really really hope Xena is not suddenly a part of the realms. :j/k:
1489	the Warrior Princess
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All this said, I find Helm's death rather ignoble and lacking, the whole setup with Tyr and Tymora odd, the removal of Mystra and Cyric strange but understandable (esp if Kellemvor is also removed / replaced), and the death of most non-greater deities (and presumably the greater 'distance' between the Prime and the (planes of the) greater deities) thought provoking. I hope the timeline does not jump 100 years as it has some much potential for interest during those hundred years (from the names of said years), but I guess we will have to wait and see. On the other hand, can you imagine the turmoil of killing off 1/2+ of the deities of Faerun? Far worse than a mere Time of Trouble, scores of religions are rendered moot, their clerics powerless, their peoples at the mercy of the suddenly crazy and hyper dangerous world around them - especially as most magic casters, spells, and items are likely no longer working due to the death / chaos of magic. Possibly the only reason magic still exists at all is due to Shar and the few Chosen still alive, acting as anchors to various tatters of what is left of the Weave. A dark time indeed . . .
I also find interesting the fact that Sune, rather like a Fey Queen creating her own Court - seems to be creating a new pantheon around herself in Brightwater. With the destruction of some many deities, it would seem that any former organization of the faerun pantheon is in tatters, and just before it became so Sune drew to herself several from diverse portfolios. I'm guessing that rather than a single all pervasive pantheon for faerun, there will be several composed of several individuals (such as Sune's) as well as several deities not really associated with any pantheon.