I started GURPS back with the 2e boxed set. I ran a fair amount of the game back in the day. Cyberpunk, superheroes, scifi, and, of course, fantasy. I loved it to pieces...until I didn't. At some point I found it kind of a sprawling mess, and didn't feel like the Compendiums went far enough. I also had a number of other issues that bothered me, and eventually gave up on it.
Now, 25 years later, I have come back to the system with 4e. While there are still things about GURPS that I am not keen on, in general I feel that 4e is a massive improvement. If feels so much more consistent. I have been buying up as much 4e stuff as my finances allow.
I am really itching to play it. I almost started up a fantasy game, but then I had group that included two newbs who wanted to get a game going, so I went for Shadow of the Weird Wizard, which I also wanted to run. But the next thing I run will very likely be GURPS. I've started working on a setting, along with how magic works.