I'm slowing down on learning new systems, as they are all blending together, and I'm finding that I'm losing system mastery on the games I play regularly. And nowadays, in quarantine gaming, 5e is almost the only game in town that is widely supported on Roll20. (PF2 is a mess on there, but I'm trying to make it work.) Forget about WHFRPG, Savage Worlds, or Forbidden Lands (games I was seriously collecting before the pandemic). Call of Cthulhu, I think, is an option on there, but I don't think it suits itself to VTT play.
I hate to be "that guy," but I believe I am going to invest about 75% of my TTRPG purchasing on 5e from now on. (Not including minis, because I still enjoy assembling and painting them, even though I'm probably not going to play in person again and use them at a real table.)