I'm in a minority here, but characters having abilities and differences based on their home or adopted region is my preferred way of dealing with "species".
Games like Legend of the Five Rings, 7th Sea, and The One Ring do it well, but they also have a much narrower scope, deal with a single well-defined world or meta-region, and all have systems where having a head-start in X at character creation based on clan/culture/home region isn't a bid deal because other characters will catch up by mid-levels (or game equivalent).
D&D tries to be uniform across several settings, has a class structure that encourages niche protection, has limited (and competing) opportunities for ASI and universal feats, and has a static skills system; none of those are favourable for integrating regionalisms in character creation. D&D deals with species the best it can, IMO, but i'd be open to setting specific variations on species. Some of those could be region-based.